Gavi, the Vaccine Alliance is a public-private global health partnership established in 2000 with the primary goal of increasing access to immunization in low- and middle-income countries. Here are key points about Gavi: - Mission and Impact: Gavi aims to save lives and protect people's health by increasing equitable and sustainable use of vaccines. It has helped immunize over 760 million children, preventing more than 13 million deaths worldwide[3][5]. - Structure and Partnerships: Gavi is a multilateral funding mechanism that brings together public and private sectors, including the World Health Organization (WHO), UNICEF, the World Bank, and vaccine manufacturers. It operates in five-year funding cycles with a revised strategy for each cycle[1][5]. - Funding and Donors: Gavi receives significant funding from industrialized countries, with the UK, the Bill & Melinda Gates Foundation, and the USA being among its largest donors. The U.S. government is the second-largest government contributor to Gavi, providing substantial financial support[1][3]. - Strategic Goals: Gavi's current strategy includes introducing and scaling up vaccines, strengthening health systems, improving programmatic and financial sustainability of immunization programs, and ensuring healthy markets for vaccines. Its next strategy, Gavi 6.0, will focus on similar goals for the 2026-2030 period[1][5]. - COVAX and COVID-19 Response: Gavi played a crucial role in COVAX, a global effort to equitably distribute COVID-19 vaccines. Although COVAX ended in 2023, COVID-19 vaccine support has been integrated into Gavi's regular programming[1].